Relationship between C-Reactive Protein Levels, Lactate Dehydrogenase, and Neutrophil-to-Lymphocyte Ratio with Coronavirus Disease 2019 Severity

Abstract: Risk stratification of Coronavirus disease 2019 (COVID-19) patients is very important to determine patient care and prognosis. The reliable parameters include C-reactive protein (CRP), lactate dehydrogenase (LDH), neutrophil-lymphocyte ratio (NLR). This study aimed the relationship between CRP, LDH, NLR levels with severity COVID-19 patients. An observational a cross-sectional approach was conducted at Ulin Hospital Banjarmasin on 91 eligible subjects. A logistic regression test variables COVID-19. results showed that there no significant CRP (prevalence odds (POR) 0.85, 95% confidence interval (CI 95%) 0.34-2.09, p=0.72). There difference mean LDH in severe compared non-severe (1006 + 601.77 vs 543.5 480.41, p<0.001), POR 4.23, CI 1.56-11.45, p=0.005; also values (9.01 6.32 5.38 5.03, p=0.002) 12.21 3.80-39.31, p<0.001. were predictors severity.